Computational Biologist – Metabolic Modelling & Deep Learning KTP Associate
University of Liverpool · Liverpool, ENG, GB
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About the role
Hours of work: Full-time
Tenure: Fixed term for 2 years
The University of Liverpool and Syngenta Limited have established a Knowledge Transfer Partnership (KTP) to recruit a specialized Computational Biologist to join Syngenta’s global R&D hub in Jealott’s Hill. This project aims to revolutionize crop protection discovery by implementing a “biology-first” approach to pathogen analysis, focusing on the development of novel methods for constructing genome-scale metabolic maps of commercially relevant pathogens. You will lead the preparation and publication of high-impact scientific papers while embedding these workflows into Syngenta’s target identification framework.
The role involves developing a species-agnostic computational pipeline that integrates cutting-edge deep learning methods—such as AlphaFold2 and FoldSeek—to enhance protein function prediction and estimate kinetic parameters for enzyme-constrained models. By processing proprietary multi-omics data, you will initially focus on determining metabolic vulnerabilities in Zymoseptoria tritici before expanding the methodology to other species to support global food security.
You should have a PhD in Computational Biology, Bioinformatics, or a related quantitative field, with proficiency in Python and a strong foundation in genome-scale metabolic modelling.
Our commitment to Equality, Diversity and Inclusion
We are committed to enhancing a workforce as diverse as our community and particularly encourage applicants who are of minoritised genders and ethnic backgrounds, living with a disability, and/or are members of the LGBTQIA+ community.
Tenure: Fixed term for 2 years
The University of Liverpool and Syngenta Limited have established a Knowledge Transfer Partnership (KTP) to recruit a specialized Computational Biologist to join Syngenta’s global R&D hub in Jealott’s Hill. This project aims to revolutionize crop protection discovery by implementing a “biology-first” approach to pathogen analysis, focusing on the development of novel methods for constructing genome-scale metabolic maps of commercially relevant pathogens. You will lead the preparation and publication of high-impact scientific papers while embedding these workflows into Syngenta’s target identification framework.
The role involves developing a species-agnostic computational pipeline that integrates cutting-edge deep learning methods—such as AlphaFold2 and FoldSeek—to enhance protein function prediction and estimate kinetic parameters for enzyme-constrained models. By processing proprietary multi-omics data, you will initially focus on determining metabolic vulnerabilities in Zymoseptoria tritici before expanding the methodology to other species to support global food security.
You should have a PhD in Computational Biology, Bioinformatics, or a related quantitative field, with proficiency in Python and a strong foundation in genome-scale metabolic modelling.
Our commitment to Equality, Diversity and Inclusion
We are committed to enhancing a workforce as diverse as our community and particularly encourage applicants who are of minoritised genders and ethnic backgrounds, living with a disability, and/or are members of the LGBTQIA+ community.
Description sourced from the public Indeed listing — this role isn't indexed from the company's career page yet.
Skills
- Python
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